(Thanks MJD for the email tip!)
Definite changes: The Reserve Wine Bar has been moved to a location between the Charlie Palmer restaurants and the Crystal Lounge Bar (replacing the "lounge" portion of the Crystal Lounge). The area formerly occupied by the Reserve is walled off and being transformed to an "Extreme Sports Lounge", with scheduled opening in July, according to a sign posted on the temporary wall. A High Limit slot area is also advertised on this wall, so there could be something else planned for the existing high limit slot area near the Comps + desk. The small Pinecone Bar near the buffet has been closed and dismantled. Not sure what will become of this area, but my guess is that it could just become more buffet tables.
Last week, an employee at the Reserve mentioned that some other near-term changes are in store for the GSR; while these are not officially confirmed they seem to be reasonable: The former Dolce is being renovated into an Italian-themed restaurant which will also be associated with Charlie Palmer. I don't remember the name but the employee said it would be open in early July and more "moderately priced" compared to CP and Fin Fish. The Reserve will be expanded to include the remainder of the lounge area in front of the CP restaurants/Cafe Sierra/Buffet area, and appetizers/cheese plates will again be available soon--now they will be on the Charlie Palmer menu.
Plans for improved ventilation for the new Reserve are also in the works. I was going to ask this employee about whether there are any plans for the former Pearl Lounge, but the wine bar was getting busy so I didn't get that chance.